منابع مشابه
Marine Toxins Targeting Ion Channels
This introductory minireview points out the importance of ion channels for cell communication. The basic concepts on the structure and function of ion channels triggered by membrane voltage changes, the so-called voltage-gated ion channels (VGICs), as well as those activated by neurotransmitters, the so-called ligand-gated ion channel (LGICs), are introduced. Among the most important VGIC super...
متن کاملSpecial Issue on Marine Toxins
The special issue on Marine Toxins of the Open Access journal Marine Drugs (ISSN 1660-3397, http://www.mdpi.com/journal/marinedrugs/) presents twenty four contributions which were received from distinguished investigators currently working in Canada, China, France, Germany, Iran, Italy, Japan, Portugal, Russian Federation, Slovenia, South Africa, Spain, and the United States. The reviews and re...
متن کاملIllnesses caused by marine toxins.
Marine toxins are produced by algae or bacteria and are concentrated in contaminated seafood. Substantial increases in seafood consumption in recent years, together with globalization of the seafood trade, have increased potential exposure to these agents. Marine toxins produce neurological, gastrointestinal, and cardiovascular syndromes, some of which result in high mortality and long-term mor...
متن کاملTOXINS: CHROMATOGRAPHY See III /MARINE TOXINS: CHROMATOGRAPHY; NEUROTOXINS: CHROMATOGRAPHY TRACE ELEMENTS BY COPRECIPITATION: EXTRACTION
substances and its interlaboratory use. Journal of Chromatography A 674: 97}126. Clauwaert KM, Van Bocxlaer JF, Lambert WE and De Leenheer AP (1997) Liquid chromatographic determination of cocaine, benzoylecgonine, and cocaethylene in whole blood and serum samples with diode-array detection. Journal of Chromatographic Science 35: 321}328. Gaillard Y and PeH pin G (1997) Use of high-performance ...
متن کاملComputational Studies of Marine Toxins Targeting Ion Channels
Toxins from marine animals offer novel drug leads for treatment of diseases involving ion channels. Computational methods could be very helpful in this endeavour in several ways, e.g., (i) constructing accurate models of the channel-toxin complexes using docking and molecular dynamics (MD) simulations; (ii) determining the binding free energies of toxins from umbrella sampling MD simulations; (...
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ژورنال
عنوان ژورنال: British Medical Bulletin
سال: 2000
ISSN: 0007-1420,1471-8391
DOI: 10.1258/0007142001902914